Varaico: Literature-Extracted Genetic Variants

GRM8

229 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 74–479UCSCReceptor family ligand binding region

NCD3Gaa 511–562UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 577–837UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 8

HGNC Alias Symbols

GLUR8; GPRC1H; mGlu8; MGLUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000845.3

p.G50D

c.149G>A

Surrounding Variants

1 paper

NM_000845.3

p.G50A

c.149G>C

1 paper

NM_000845.3

p.G50delFs

c.149delC

1 paper

NM_000845.3

p.G50fs

c.148_149fs

1 paper

NM_000845.3

p.G49E

c.146G>A

2 papers

NM_000845.3

p.L48*

c.143T>A

1 paper

NM_000845.3

p.H55delFs

c.163delG

1 paper

NM_000845.3

p.A56T

c.166G>A

2 papers

NM_000845.3

p.G58R

c.172G>C

2 papers

NM_000845.3

p.G58R

c.172G>A

1 paper

NM_000845.3

p.V42G

c.125T>G

1 paper

NM_000845.3

p.G58E

c.173G>A

1 paper

NM_000845.3

p.R41P

c.122G>C