Varaico: Literature-Extracted Genetic Variants

Gene:GRXCR1
Variant:p.Q77*

GRXCR1

96 papers

RefSeq Summary

This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutath...

Pfam Domains

Glutaredoxinaa 139–208UCSCGlutaredoxin
GRXCR1-2_Caa 239–289UCSCGRXCR1/2, C-terminal domain

Gene Aliases

HGNC Name

glutaredoxin and cysteine rich domain containing 1

HGNC Previous Symbol

DFNB25

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_001080476.3
p.Q77*
c.229C>T
Surrounding Variants
1 paper
NM_001080476.3
p.Q77H
c.231G>C
1 paper
NM_001080476.3
p.Q77H
c.231G>T
2 papers
NM_001080476.3
p.A86G
c.257C>G
3 papers
NM_001080476.3
p.G64S
c.190G>A
1 paper
NM_001080476.3
p.G91S
c.271G>A
5 papers
NM_001080476.3
p.G91V
c.272G>T
1 paper
NM_001080476.3
p.Q62R
c.185A>G
1 paper
NM_001080476.3
p.Q61K
c.181C>A
1 paper
NM_001080476.3
p.G60R
c.178G>A
1 paper
NM_001080476.3
p.G60R
c.178G>C
1 paper
NM_001080476.3
p.D59G
c.176A>G
1 paper
NM_001080476.3
p.D59N
c.175G>A
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