Varaico: Literature-Extracted Genetic Variants

GSR

218 papers

RefSeq Summary

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and re...

Pfam Domains

FAD_oxidoredaa 66–201UCSCFAD dependent oxidoreductase

Pyr_redoxaa 233–313UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 411–522UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

glutathione-disulfide reductase

HGNC Alias Symbol

GRase

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000637.5

p.P213S

c.637C>T

Surrounding Variants

1 paper

NM_000637.5

p.H208N

c.622C>A

1 paper

NM_000637.5

p.T206N

c.617C>A

1 paper

NM_000637.5

p.T206P

c.616A>C

1 paper

NM_000637.5

p.G202G

c.606T>C

1 paper

NM_000637.5

p.T200T

c.600A>G

1 paper

NM_000637.5

p.A199T

c.595G>A

1 paper

NM_000637.5

p.I198M

c.594C>G

1 paper

NM_000637.5

p.L197L

c.589C>T

1 paper

NM_000637.5

p.T192S

c.575C>G

1 paper

NM_000637.5

p.T192S

c.574A>T

1 paper

NM_000637.5

p.T192A

c.574A>G

2 papers

NM_000637.5

p.S187T

c.560G>C