Varaico: Literature-Extracted Genetic Variants

GTF2A2

39 papers

RefSeq Summary

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963)...

Pfam Domains

TFIIA_gamma_Naa 2–48UCSCTranscription initiation factor IIA, gamma subunit, helical domain

TFIIA_gamma_Caa 59–100UCSCTranscription initiation factor IIA, gamma subunit

Gene Aliases

HGNC Name

general transcription factor IIA subunit 2

HGNC Alias Symbols

TFIIA; HsT18745

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004492.3

p.E109A

c.326A>C

Surrounding Variants

1 paper

NM_004492.3

p.G104fs

c.310_311fs

1 paper

NM_004492.3

p.N102_T103insFs

c.305_309dup5

1 paper

NM_004492.3

p.I95T

c.284T>C

1 paper

NM_004492.3

p.V93M

c.277G>A

1 paper

NM_004492.3

p.D91A

c.272A>C

1 paper

NM_004492.3

p.L76P

c.227T>C

1 paper

NM_004492.3

p.L76fs

c.226_227fs

1 paper

NM_004492.3

p.T73A

c.217A>G

1 paper

NM_004492.3

p.V71M

c.211G>A

2 papers

NM_004492.3

p.Y65F

c.194A>T

1 paper

NM_004492.3

p.T64T

c.192G>A

1 paper

NM_004492.3

p.T64A

c.190A>G