Varaico: Literature-Extracted Genetic Variants

Gene:GZMM
Variant:p.R221G

GZMM

45 papers

RefSeq Summary

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytop...

Pfam Domains

Trypsinaa 1–210UCSCTrypsin

Gene Aliases

HGNC Name

granzyme M

HGNC Alias Symbols

MET1; LMET1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_005317.4
p.R221G
c.661A>G
Surrounding Variants
2 papers
NM_005317.4
p.R217Q
c.650G>A
1 paper
NM_005317.4
p.P236_P237delFs
c.708_709delTC
1 paper
NM_005317.4
p.P237_V238insFs
c.711_712insTG
1 paper
NM_005317.4
p.A241delFs
c.721delG
1 paper
NM_005317.4
p.Y245*
c.735C>A
1 paper
NM_005317.4
p.Y245*
c.735C>G
1 paper
NM_005317.4
p.R255_S256delFs
c.765_768del4
1 paper
NM_005317.4
p.R255*
c.763C>T
1 paper
NM_005317.4
p.C203insFs
c.607dupT
2 papers
NM_005317.4
p.Q200*
c.598C>T
1 paper
NM_005317.4
p.K198Fs
c.594delinsCGFs
1 paper
NM_005317.4
p.D196Y
c.586G>T
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