Varaico: Literature-Extracted Genetic Variants

Gene:H2AX
Variant:p.T7T

H2AX

319 papers

RefSeq Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) for...

Pfam Domains

Histoneaa 4–90UCSCCore histone H2A/H2B/H3/H4 domain
Histone_H2A_Caa 92–126UCSCC-terminus of histone H2A

Gene Aliases

HGNC Name

H2A.X variant histone

HGNC Previous Symbol

H2AFX

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002105.3
p.T7T
c.21T>A
Surrounding Variants
1 paper
NM_002105.3
p.G8D
c.23G>A
1 paper
NM_002105.3
p.G9S
c.25G>A
3 papers
NM_002105.3
p.K6R
c.17A>G
1 paper
NM_002105.3
p.K10R
c.29A>G
1 paper
NM_002105.3
p.R4R
c.12C>T
1 paper
NM_002105.3
p.G3G
c.9C>T
1 paper
NM_002105.3
p.G3fs
c.7_8fs
2 papers
NM_002105.3
p.R12S
c.34C>A
1 paper
NM_002105.3
p.G3S
c.7G>A
2 papers
NM_002105.3
p.M1insFs
c.2_3insT
1 paper
NM_002105.3
p.K14R
c.41A>G
1 paper
NM_002105.3
p.M1V
c.1A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."