Varaico: Literature-Extracted Genetic Variants

HCK

112 papers

RefSeq Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help cou...

Pfam Domains

SH3_1aa 84–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 262–511UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

HCK proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK9

Papers

RefSeq ID

Protein change

DNA change

1–12 of 138 variants

3 papers

NM_002110.5

p.R156C

c.466C>T

3 papers

NM_002110.5

p.S183Y

c.548C>A

3 papers

NM_002110.5

p.K290E

c.868A>G

3 papers

NM_002110.5

p.V299L

c.895G>C

3 papers

NM_002110.5

p.V299L

c.895G>T

3 papers

NM_002110.5

p.E410K

c.1228G>A

3 papers

NM_002110.5

p.Y515*

c.1545C>A

3 papers

NM_002110.5

p.Y515*

c.1545C>G

2 papers

NM_002110.5

p.D15V

c.44A>T

2 papers

NM_002110.5

p.A44T

c.130G>A

2 papers

NM_002110.5

p.M105L

c.313A>C

2 papers

NM_002110.5

p.M105L

c.313A>T