Varaico: Literature-Extracted Genetic Variants

HCK

112 papers

RefSeq Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help cou...

Pfam Domains

SH3_1aa 84–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 262–511UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

HCK proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002110.5

p.S45_P46delins

c.135_136delinsTG

Surrounding Variants

1 paper

NM_002110.5

p.P46A

c.136C>G

2 papers

NM_002110.5

p.A44T

c.130G>A

1 paper

NM_002110.5

p.N35S

c.104A>G

1 paper

NM_002110.5

p.Q31L

c.92A>T

1 paper

NM_002110.5

p.N64Y

c.190A>T

1 paper

NM_002110.5

p.I73V

c.217A>G

1 paper

NM_002110.5

p.A76V

c.227C>T

1 paper

NM_002110.5

p.A76A

c.228A>T

1 paper

NM_002110.5

p.E79K

c.235G>A

1 paper

NM_002110.5

p.E79G

c.236A>G

1 paper

NM_002110.5

p.A85T

c.253G>A

1 paper

NM_002110.5

p.A85V

c.254C>T