Varaico: Literature-Extracted Genetic Variants

HCK

112 papers

RefSeq Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help cou...

Pfam Domains

SH3_1aa 84–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 262–511UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

HCK proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002110.5

p.D204Y

c.610G>T

Surrounding Variants

1 paper

NM_002110.5

p.D204G

c.611A>G

1 paper

NM_002110.5

p.N205H

c.613A>C

1 paper

NM_002110.5

p.K199Q

c.595A>C

1 paper

NM_001172129.3

p.V174M

c.520G>A

1 paper

NM_002110.5

p.R190Q

c.569G>A

1 paper

NM_002110.5

p.Q220K

c.658C>A

1 paper

NM_002110.5

p.D188N

c.562G>A

1 paper

NM_002110.5

p.L222M

c.664C>A

1 paper

NM_002110.5

p.D224N

c.670G>A

1 paper

NM_002110.5

p.S183S

c.549C>A

3 papers

NM_002110.5

p.S183Y

c.548C>A

1 paper

NM_002110.5

p.S183P

c.547T>C