Varaico: Literature-Extracted Genetic Variants

HCK

112 papers

RefSeq Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help cou...

Pfam Domains

SH3_1aa 84–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 262–511UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

HCK proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002110.5

p.V287L

c.859G>T

Surrounding Variants

1 paper

NM_002110.5

p.V287L

c.859G>C

1 paper

NM_002110.5

p.A288V

c.863C>T

1 paper

NM_002110.5

p.A288A

c.864A>G

3 papers

NM_002110.5

p.K290E

c.868A>G

1 paper

NM_002110.5

p.K290N

c.870G>C

1 paper

NM_002110.5

p.K290N

c.870G>T

1 paper

NM_002110.5

p.T291P

c.871A>C

1 paper

NM_002110.5

p.N282N

c.846C>T

1 paper

NM_002110.5

p.T291T

c.873G>C

1 paper

NM_002110.5

p.M297L

c.889A>C

1 paper

NM_002110.5

p.M297L

c.889A>T

3 papers

NM_002110.5

p.V299L

c.895G>C