Varaico: Literature-Extracted Genetic Variants

HCK

112 papers

RefSeq Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help cou...

Pfam Domains

SH3_1aa 84–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 262–511UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

HCK proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002110.5

p.M309L

c.925A>C

Surrounding Variants

1 paper

NM_002110.5

p.M309L

c.925A>T

1 paper

NM_002110.5

p.K310E

c.928A>G

1 paper

NM_002110.5

p.E305A

c.914A>C

1 paper

NM_002110.5

p.F302L

c.906C>A

1 paper

NM_002110.5

p.F302L

c.906C>G

1 paper

NM_002110.5

p.F302L

c.904T>C

1 paper

NM_002110.5

p.E300K

c.898G>A

3 papers

NM_002110.5

p.V299L

c.895G>C

3 papers

NM_002110.5

p.V299L

c.895G>T

2 papers

NM_002110.5

p.L320F

c.958C>T

1 paper

NM_002110.5

p.M297L

c.889A>C

1 paper

NM_002110.5

p.M297L

c.889A>T