Varaico: Literature-Extracted Genetic Variants

HCK

112 papers

RefSeq Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help cou...

Pfam Domains

SH3_1aa 84–130UCSCSH3 domain

SH2aa 144–226UCSCSH2 domain

PK_Tyr_Ser-Thraa 262–511UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

HCK proto-oncogene, Src family tyrosine kinase

HGNC Alias Symbol

JTK9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002110.5

p.Y522F

c.1565A>T

Surrounding Variants

3 papers

NM_002110.5

p.Y515*

c.1545C>A

3 papers

NM_002110.5

p.Y515*

c.1545C>G

1 paper

NM_002110.5

p.Q508H

c.1524G>C

1 paper

NM_002110.5

p.Q508H

c.1524G>T

1 paper

NM_002110.5

p.E500V

c.1499A>T

1 paper

NM_002110.5

p.E499K

c.1495G>A

1 paper

NM_002110.5

p.R492L

c.1475G>T

1 paper

NM_001172129.3

p.P456H

c.1367C>A

1 paper

NM_002110.5

p.R475Q

c.1424G>A

1 paper

NM_002110.5

p.L470M

c.1408C>A

1 paper

NM_002110.5

p.E465*

c.1393G>T

1 paper

NM_002110.5

p.G460E

c.1379G>A