Varaico: Literature-Extracted Genetic Variants

HCN1

326 papers

RefSeq Summary

The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize o...

Pfam Domains

Ion_trans_Naa 98–141UCSCIon transport protein N-terminal

Ion_transaa 142–405UCSCIon transport protein

cNMP_bindingaa 493–576UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

hyperpolarization activated cyclic nucleotide gated potassium channel 1

HGNC Previous Symbol

BCNG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021072.4

p.V381V

c.1143C>G

Surrounding Variants

1 paper

NM_021072.4

p.V381V

c.1143C>A

3 papers

NM_021072.4

p.G382A

c.1145G>C

4 papers

NM_021072.4

p.I380N

c.1139T>A

10 papers

NM_021072.4

p.I380F

c.1138A>T

3 papers

NM_021072.4

p.M379R

c.1136T>G

7 papers

NM_021072.4

p.A387S

c.1159G>T

1 paper

NM_021072.4

p.M388K

c.1163T>A

1 paper

NM_021072.4

p.F389S

c.1166T>C

1 paper

NM_021072.4

p.F389Y

c.1166T>A

1 paper

NM_021072.4

p.F389F

c.1167T>C

1 paper

NM_021072.4

p.V390I

c.1168G>A

2 papers

NM_021072.4

p.V390A

c.1169T>C