Varaico: Literature-Extracted Genetic Variants

HCN1

326 papers

RefSeq Summary

The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize o...

Pfam Domains

Ion_trans_Naa 98–141UCSCIon transport protein N-terminal

Ion_transaa 142–405UCSCIon transport protein

cNMP_bindingaa 493–576UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

hyperpolarization activated cyclic nucleotide gated potassium channel 1

HGNC Previous Symbol

BCNG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021072.4

p.F325S

c.974T>C

Surrounding Variants

1 paper

NM_021072.4

p.D328E

c.984T>G

1 paper

NM_021072.4

p.D328E

c.984T>A

7 papers

NM_021072.4

p.C329S

c.985T>A

7 papers

NM_021072.4

p.C329S

c.986G>C

1 paper

NM_021072.4

p.W330*

c.989G>A

2 papers

NM_021072.4

p.W330C

c.990G>T

2 papers

NM_021072.4

p.W330C

c.990G>C

1 paper

NM_021072.4

p.W330*

c.990G>A

1 paper

NM_021072.4

p.L318*

c.953T>A

1 paper

NM_021072.4

p.C314S

c.941G>C

1 paper

NM_021072.4

p.C314S

c.940T>A

1 paper

NM_021072.4

p.H310Y

c.928C>T