Varaico: Literature-Extracted Genetic Variants

HCN1

326 papers

RefSeq Summary

The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize o...

Pfam Domains

Ion_trans_Naa 98–141UCSCIon transport protein N-terminal

Ion_transaa 142–405UCSCIon transport protein

cNMP_bindingaa 493–576UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

hyperpolarization activated cyclic nucleotide gated potassium channel 1

HGNC Previous Symbol

BCNG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021072.4

p.V223_V224ins9

c.667_671ins27

Surrounding Variants

1 paper

NM_021072.4

p.V223_V224insGCG

c.667_671ins9

1 paper

NM_021072.4

p.V223_V224ins6

c.667_671ins18

2 papers

NM_021072.4

p.W221_V223del3

c.661_668del9

1 paper

NM_021072.4

p.L218_V223del6

c.652_668del18

1 paper

NM_021072.4

p.I213F

c.637A>T

1 paper

NM_021072.4

p.D233G

c.698A>G

4 papers

NM_021072.4

p.D233A

c.698A>C

1 paper

NM_021072.4

p.D233E

c.699T>G

1 paper

NM_021072.4

p.D233E

c.699T>A

1 paper

NM_021072.4

p.D202_P210del9

c.604_629del27

1 paper

NM_021072.4

p.E201_D209del9

c.601_626del27

1 paper

NM_021072.4

p.D202_I207del6

c.604_620del18