Varaico: Literature-Extracted Genetic Variants

HCN2

165 papers

RefSeq Summary

The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated...

Pfam Domains

Ion_trans_Naa 167–210UCSCIon transport protein N-terminal

Ion_transaa 211–474UCSCIon transport protein

cNMP_bindingaa 562–645UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

HGNC Previous Symbol

BCNG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001194.4

p.P790R

c.2369C>G

Surrounding Variants

1 paper

NM_001194.4

p.G796C

c.2386G>T

3 papers

NM_001194.4

p.P802S

c.2404C>T

1 paper

NM_001194.4

p.P802L

c.2405C>T

1 paper

NM_001194.4

p.R756C

c.2266C>T

2 papers

NM_001194.4

p.A751A

c.2253G>C

1 paper

NM_001194.4

p.A841G

c.2522C>G

4 papers

NM_001194.4

p.F738C

c.2213T>G

1 paper

NM_001194.4

p.M736I

c.2208G>A

1 paper

NM_001194.4

p.M736I

c.2208G>C

1 paper

NM_001194.4

p.M736I

c.2208G>T

1 paper

NM_001194.4

p.A728delFs

c.2184delC

2 papers

NM_001194.4

p.P721L

c.2162C>T