Varaico: Literature-Extracted Genetic Variants

HCN4

399 papers

RefSeq Summary

This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for t...

Pfam Domains

Ion_trans_Naa 218–261UCSCIon transport protein N-terminal

Ion_transaa 262–525UCSCIon transport protein

cNMP_bindingaa 613–696UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

hyperpolarization activated cyclic nucleotide gated potassium channel 4

HGNC Previous Name

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

18 papers

NM_005477.3

p.V759I

c.2275G>A

Surrounding Variants

1 paper

NM_005477.3

p.A756T

c.2266G>A

1 paper

NM_005477.3

p.H754Y

c.2260C>T

1 paper

NM_005477.3

p.M752I

c.2256G>T

1 paper

NM_005477.3

p.M752I

c.2256G>C

2 papers

NM_005477.3

p.M752I

c.2256G>A

1 paper

NM_005477.3

p.A765G

c.2294C>G

1 paper

NM_005477.3

p.T766A

c.2296A>G

1 paper

NM_005477.3

p.T770M

c.2309C>T

1 paper

NM_005477.3

p.V772I

c.2314G>A

2 papers

NM_005477.3

p.P776L

c.2327C>T

1 paper

NM_005477.3

p.L777R

c.2330T>G

1 paper

NM_005477.3

p.N739K

c.2217T>G