Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.Y27C

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001525.3
p.Y27C
c.80A>G
Surrounding Variants
1 paper
NM_001525.3
p.Y27D
c.79T>G
1 paper
NM_001525.3
p.E28K
c.82G>A
1 paper
NM_001525.3
p.D29N
c.85G>A
1 paper
NM_001525.3
p.P25L
c.74C>T
1 paper
NM_001525.3
p.D29E
c.87T>A
1 paper
NM_001525.3
p.D29E
c.87T>G
1 paper
NM_001525.3
p.P24R
c.71C>G
1 paper
NM_001525.3
p.P24L
c.71C>T
1 paper
NM_001525.3
p.F31L
c.91T>C
1 paper
NM_001525.3
p.V23A
c.68T>C
1 paper
NM_001525.3
p.F31C
c.92T>G
1 paper
NM_001525.3
p.F31L
c.93T>A
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