Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.K43*

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001525.3
p.K43*
c.127A>T
Surrounding Variants
1 paper
NM_001525.3
p.P42A
c.124C>G
1 paper
NM_001525.3
p.Q44P
c.131A>C
1 paper
NM_001525.3
p.Y41H
c.121T>C
1 paper
NM_001525.3
p.Y45C
c.134A>G
1 paper
NM_001525.3
p.E46V
c.137A>T
1 paper
NM_001525.3
p.Y39F
c.116A>T
1 paper
NM_001525.3
p.W47R
c.139T>A
1 paper
NM_001525.3
p.W47R
c.139T>C
1 paper
NM_001525.3
p.D38G
c.113A>G
2 papers
NM_001525.3
p.D38N
c.112G>A
5 papers
NM_001525.3
p.R37R
c.111C>T
4 papers
NM_001525.3
p.R37H
c.110G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."