Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.R260H

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001525.3
p.R260H
c.779G>A
Surrounding Variants
1 paper
NM_001525.3
p.R260C
c.778C>T
1 paper
NM_001525.3
p.K259R
c.776A>G
1 paper
NM_001525.3
p.K259E
c.775A>G
1 paper
NM_001525.3
p.D263A
c.788A>C
1 paper
NM_001525.3
p.Q264P
c.791A>C
1 paper
NM_001525.3
p.R256Q
c.767G>A
1 paper
NM_001525.3
p.R256W
c.766C>T
1 paper
NM_001525.3
p.Q264H
c.792G>C
1 paper
NM_001525.3
p.Q264H
c.792G>T
3 papers
NM_001525.3
p.L265M
c.793C>A
1 paper
NM_001525.3
p.D267N
c.799G>A
1 paper
NM_001525.3
p.L268V
c.802C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."