Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.E275D

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001525.3
p.E275D
c.825G>C
Surrounding Variants
1 paper
NM_001525.3
p.E275D
c.825G>T
1 paper
NM_001525.3
p.P276L
c.827C>T
1 paper
NM_001525.3
p.E275K
c.823G>A
1 paper
NM_001525.3
p.E275Q
c.823G>C
1 paper
NM_001525.3
p.G274E
c.821G>A
1 paper
NM_001525.3
p.S273R
c.819T>A
1 paper
NM_001525.3
p.S273R
c.819T>G
1 paper
NM_001525.3
p.S273N
c.818G>A
1 paper
NM_001525.3
p.S273R
c.817A>C
1 paper
NM_001525.3
p.R279W
c.835C>T
4 papers
NM_001525.3
p.R279Q
c.836G>A
1 paper
NM_001525.3
p.R279R
c.837G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."