Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.R366W

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001525.3
p.R366W
c.1096C>T
Surrounding Variants
1 paper
NM_001525.3
p.R366Q
c.1097G>A
1 paper
NM_001525.3
p.R366P
c.1097G>C
1 paper
NM_001525.3
p.E367K
c.1099G>A
1 paper
NM_001525.3
p.E367V
c.1100A>T
1 paper
NM_001525.3
p.F369L
c.1105T>C
1 paper
NM_001525.3
p.F369L
c.1107T>A
1 paper
NM_001525.3
p.F369L
c.1107T>G
1 paper
NM_001525.3
p.K370N
c.1110G>C
1 paper
NM_001525.3
p.K370N
c.1110G>T
1 paper
NM_001525.3
p.A372D
c.1115C>A
1 paper
NM_001525.3
p.A372V
c.1115C>T
1 paper
NM_001525.3
p.S374del1
c.1120_1121delTCC
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."