Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.P389A

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001525.3
p.P389A
c.1165C>G
Surrounding Variants
1 paper
NM_001525.3
p.A388G
c.1163C>G
1 paper
NM_001525.3
p.S390G
c.1168A>G
1 paper
NM_001525.3
p.S390T
c.1169G>C
1 paper
NM_001525.3
p.R392S
c.1174C>A
1 paper
NM_001525.3
p.R392G
c.1174C>G
1 paper
NM_001525.3
p.R392C
c.1174C>T
1 paper
NM_001525.3
p.R392H
c.1175G>A
1 paper
NM_001525.3
p.R392L
c.1175G>T
1 paper
NM_001525.3
p.S393F
c.1178C>T
1 paper
NM_001525.3
p.G384S
c.1150G>A
1 paper
NM_001525.3
p.A395T
c.1183G>A
1 paper
NM_001525.3
p.A395P
c.1183G>C
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