Varaico: Literature-Extracted Genetic Variants

Gene:HCRTR1
Variant:p.V416M

HCRTR1

79 papers

RefSeq Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related...

Pfam Domains

7tm_1aa 63–358UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

hypocretin receptor 1

HGNC Alias Symbols

OX1R; ORXR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_001525.3
p.V416M
c.1246G>A
Surrounding Variants
1 paper
NM_001525.3
p.V415M
c.1243G>A
1 paper
NM_001525.3
p.V415L
c.1243G>C
1 paper
NM_001525.3
p.V415L
c.1243G>T
1 paper
NM_001525.3
p.H414R
c.1241A>G
1 paper
NM_001525.3
p.H414D
c.1240C>G
1 paper
NM_001525.3
p.T418N
c.1253C>A
1 paper
NM_001525.3
p.V420I
c.1258G>A
1 paper
NM_001525.3
p.V420L
c.1258G>C
1 paper
NM_001525.3
p.I411T
c.1232T>C
1 paper
NM_001525.3
p.K410T
c.1229A>C
1 paper
NM_001525.3
p.T422K
c.1265C>A
1 paper
NM_001525.3
p.T422R
c.1265C>G
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