Varaico: Literature-Extracted Genetic Variants

Gene:HDAC1
Variant:p.M1L

HDAC1

495 papers

RefSeq Summary

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone dea...

Pfam Domains

Hist_deacetylaa 28–319UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 1

HGNC Previous Symbol

RPD3L1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004964.3
p.M1L
c.1A>C
Surrounding Variants
2 papers
NM_004964.3
p.M1insFs
c.2_3insT
1 paper
NM_004964.3
p.M1V
c.1A>G
1 paper
NM_004964.3
p.M1L
c.1A>T
1 paper
NM_004964.3
p.M1_R9del9
c.1_26del27
1 paper
NM_004964.3
p.M1_A2insFs
c.3_4insA
1 paper
NM_004964.3
p.M1_Q3del0
c.1_9del9
1 paper
NM_004964.3
p.A2T
c.4G>A
1 paper
NM_004964.3
p.A2G
c.5C>G
1 paper
NM_004964.3
p.A2V
c.5C>T
1 paper
NM_004964.3
p.Q3insFs
c.7dupC
1 paper
NM_004964.3
p.T4R
c.11C>G
1 paper
NM_004964.3
p.T4T
c.12G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."