Varaico: Literature-Extracted Genetic Variants

Gene:HDAC1
Variant:p.K289E

HDAC1

495 papers

RefSeq Summary

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone dea...

Pfam Domains

Hist_deacetylaa 28–319UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 1

HGNC Previous Symbol

RPD3L1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004964.3
p.K289E
c.865A>G
Surrounding Variants
1 paper
NM_004964.3
p.K289N
c.867G>C
1 paper
NM_004964.3
p.K289N
c.867G>T
1 paper
NM_004964.3
p.F287Y
c.860T>A
1 paper
NM_004964.3
p.C284Y
c.851G>A
1 paper
NM_004964.3
p.M295insFs
c.883dupA
3 papers
NM_004964.3
p.A282T
c.844G>A
1 paper
NM_004964.3
p.H281H
c.843C>T
1 paper
NM_004964.3
p.G280E
c.839G>A
1 paper
NM_004964.3
p.M297I
c.891G>A
1 paper
NM_004964.3
p.M297I
c.891G>C
1 paper
NM_004964.3
p.M297I
c.891G>T
1 paper
NM_004964.3
p.G301S
c.901G>A
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