Varaico: Literature-Extracted Genetic Variants

Gene:HDAC3
Variant:p.L266M

HDAC3

225 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 22–314UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 3

HGNC Alias Symbols

RPD3; HD3; RPD3-2; KDAC3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003883.4
p.L266M
c.796T>A
Surrounding Variants
5 papers
NM_003883.4
p.L266S
c.797T>C
1 paper
NM_003883.4
p.R265P
c.794G>C
1 paper
NM_003883.4
p.G267S
c.799G>A
1 paper
NM_003883.4
p.G257E
c.770G>A
3 papers
NM_003883.4
p.L254P
c.761T>C
1 paper
NM_003883.4
p.K233insFs
c.697_698insA
1 paper
NM_003883.4
p.K233R
c.698A>G
1 paper
NM_003883.4
p.N220Y
c.658A>T
1 paper
NM_003883.4
p.G214G
c.642C>G
1 paper
NM_003883.4
p.S213I
c.638G>T
2 papers
NM_003883.4
p.P201S
c.601C>T
1 paper
NM_003883.4
p.N197K
c.591T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."