Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001378414.1

p.V759I

c.2275G>A

Surrounding Variants

1 paper

NM_001378414.1

p.L778_A779del2

c.2332_2336del6

1 paper

NM_001378414.1

p.A791_T792insFs

c.2373_2374insG

4 papers

NM_001378414.1

p.A800insFs

c.2399_2400insC

2 papers

NM_006037.4

p.P800insFs

c.2399_2400insC

1 paper

NM_006037.4

p.G801fs

c.2401_2402fs

1 paper

NM_001378414.1

p.K737Q

c.2209A>C

1 paper

NM_001378414.1

p.R735Q

c.2204G>A

1 paper

NM_001378414.1

p.Y728*

c.2184T>G

1 paper

NM_001378414.1

p.Y728*

c.2184T>A