Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001378414.1

p.Y728*

c.2184T>G

Surrounding Variants

1 paper

NM_001378414.1

p.Y728*

c.2184T>A

1 paper

NM_001378414.1

p.R735Q

c.2204G>A

1 paper

NM_001378414.1

p.K737Q

c.2209A>C

1 paper

NM_001378414.1

p.G698G

c.2094C>T

1 paper

NM_001378414.1

p.E696*

c.2086G>T

1 paper

NM_001378414.1

p.G660V

c.1979G>T

1 paper

NM_001378414.1

p.V759I

c.2275G>A

1 paper

NM_001378414.1

p.E650D

c.1950G>T

1 paper

NM_001378414.1

p.E650D

c.1950G>C

1 paper

NM_001378414.1

p.E650V

c.1949A>T

1 paper

NM_001378414.1

p.R630R

c.1890G>A

1 paper

NM_001378414.1

p.G627V

c.1880G>T