Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001378414.1

p.G220R

c.658G>C

Surrounding Variants

4 papers

NM_001378414.1

p.G220R

c.658G>A

1 paper

NM_001378414.1

p.T223A

c.667A>G

3 papers

NM_001378414.1

p.T223T

c.669C>A

1 paper

NM_001378414.1

p.H227R

c.680A>G

1 paper

NM_001378414.1

p.S210A

c.628T>G

2 papers

NM_001378414.1

p.M232I

c.696G>C

1 paper

NM_001378414.1

p.D234N

c.700G>A

1 paper

NM_001378414.1

p.G204R

c.610G>C

1 paper

NM_001378414.1

p.G204R

c.610G>A

1 paper

NM_001378414.1

p.L241F

c.721C>T

1 paper

NM_001378414.1

p.T244K

c.731C>A

1 paper

NM_001378414.1

p.G204R

c.610G>A