Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001378414.1

p.E177K

c.529G>A

Surrounding Variants

1 paper

NM_001378414.1

p.V179D

c.536T>A

1 paper

NM_001378414.1

p.L180V

c.538C>G

1 paper

NM_001378414.1

p.M173T

c.518T>C

1 paper

NM_001378414.1

p.K182R

c.545A>G

4 papers

NM_001378414.1

p.A185V

c.554C>T

1 paper

NM_001378414.1

p.A167G

c.500C>G

1 paper

NM_001378414.1

p.A167P

c.499G>C

1 paper

NM_001378414.1

p.H188R

c.563A>G

1 paper

NM_001378414.1

p.R189W

c.565C>T

1 paper

NM_001378414.1

p.N190S

c.569A>G

1 paper

NM_001378414.1

p.S164Splc

c.491-6C>T

1 paper

NM_001378414.1

p.C194G

c.580T>G