Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001378414.1

p.Q107*

c.319C>T

Surrounding Variants

1 paper

NM_001378414.1

p.Q107E

c.319C>G

1 paper

NM_001378414.1

p.Q96_A106delFs

c.287_317del31

1 paper

NM_001378414.1

p.E105K

c.313G>A

1 paper

NM_001378414.1

p.E110_H111ins8

c.328_332ins24

1 paper

NM_001378414.1

p.Q103L

c.308A>T

1 paper

NM_001378414.1

p.K113Q

c.337A>C

1 paper

NM_001378414.1

p.E98K

c.292G>A

1 paper

NM_001378414.1

p.Q94L

c.281A>T

1 paper

NM_001378414.1

p.I90I

c.270C>T

2 papers

NM_001378414.1

p.I88V

c.262A>G

1 paper

NM_001378414.1

p.R86R

c.256A>C

1 paper

NM_001378414.1

p.Q82R

c.245A>G