Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001378414.1

p.H55R

c.164A>G

Surrounding Variants

1 paper

NM_001378414.1

p.F57L

c.169T>C

1 paper

NM_001378414.1

p.L53L

c.159G>C

1 paper

NM_001378414.1

p.F57L

c.171C>G

1 paper

NM_001378414.1

p.F57L

c.171C>A

1 paper

NM_001378414.1

p.R52insFs

c.155_156ins5

2 papers

NM_001378414.1

p.R52H

c.155G>A

1 paper

NM_001378414.1

p.A37_L51del15

c.109_152del45

1 paper

NM_001378414.1

p.L59L

c.177G>T

1 paper

NM_001378414.1

p.D50Y

c.148G>T

1 paper

NM_001378414.1

p.P48T

c.142C>A

1 paper

NM_001378414.1

p.P64L

c.191C>T

1 paper

NM_001378414.1

p.A65P

c.193G>C