Varaico: Literature-Extracted Genetic Variants

HDAC4

311 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 62–152UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 675–992UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 4

HGNC Previous Symbol

BDMR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001378414.1

p.P16T

c.46C>A

Surrounding Variants

1 paper

NM_001378414.1

p.V17M

c.49G>A

1 paper

NM_001378414.1

p.R13_V17del0

c.37_51del15

2 papers

NM_001378414.1

p.G12V

c.35G>T

1 paper

NM_001378414.1

p.G12D

c.35G>A

1 paper

NM_001378414.1

p.G12C

c.34G>T

1 paper

NM_001378414.1

p.L10insFs

c.29_30insC

1 paper

NM_001378414.1

p.P22T

c.64C>A

1 paper

NM_001378414.1

p.R24C

c.70C>T

1 paper

NM_001378414.1

p.T31fs

c.91_92fs

2 papers

NM_001378414.1

p.T31T

c.93G>A