Varaico: Literature-Extracted Genetic Variants

HDAC5

138 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 67–164UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 704–1022UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 5

HGNC Alias Symbols

KIAA0600; NY-CO-9; FLJ90614

Papers

RefSeq ID

Protein change

DNA change

1–12 of 98 variants

9 papers

NM_005474.5

p.S259A

c.775T>G

8 papers

NM_005474.5

p.S498A

c.1492T>G

4 papers

NM_005474.5

p.D594E

c.1782T>G

4 papers

NM_005474.5

p.D594E

c.1782T>A

2 papers

NM_005474.5

p.E14Q

c.40G>C

2 papers

NM_005474.5

p.Q128R

c.383A>G

2 papers

NM_005474.5

p.S309F

c.926C>T

2 papers

NM_005474.5

p.P322A

c.964C>G

2 papers

NM_005474.5

p.E591G

c.1772A>G

2 papers

NM_005474.5

p.D593E

c.1779C>G

2 papers

NM_005474.5

p.D593E

c.1779C>A

2 papers

NM_005474.5

p.S886Y

c.2657C>A