Varaico: Literature-Extracted Genetic Variants

HDAC5

138 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 67–164UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 704–1022UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 5

HGNC Alias Symbols

KIAA0600; NY-CO-9; FLJ90614

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005474.5

p.S886Y

c.2657C>A

Surrounding Variants

1 paper

NM_005474.5

p.P885H

c.2654C>A

1 paper

NM_005474.5

p.W924L

c.2771G>T

1 paper

NM_005474.5

p.W924C

c.2772G>T

1 paper

NM_005474.5

p.W924C

c.2772G>C

1 paper

NM_005474.5

p.D929fs

c.2785_2786fs

1 paper

NM_005474.5

p.D929insFs

c.2787dupC

1 paper

NM_005474.5

p.F983insFs

c.2947_2948ins23

2 papers

NM_005474.5

p.H1006Y

c.3016C>T

1 paper

NM_005474.5

p.T838K

c.2513C>A

1 paper

NM_005474.5

p.E836K

c.2506G>A

1 paper

NM_005474.5

p.A1102V

c.3305C>T

1 paper

NM_005474.5

p.A1103V

c.3308C>T