Varaico: Literature-Extracted Genetic Variants

HDAC5

138 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 67–164UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 704–1022UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 5

HGNC Alias Symbols

KIAA0600; NY-CO-9; FLJ90614

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005474.5

p.D593E

c.1779C>G

Surrounding Variants

2 papers

NM_005474.5

p.D593E

c.1779C>A

4 papers

NM_005474.5

p.D594E

c.1782T>G

4 papers

NM_005474.5

p.D594E

c.1782T>A

2 papers

NM_005474.5

p.E591G

c.1772A>G

1 paper

NM_005474.5

p.E589E

c.1767G>A

1 paper

NM_005474.5

p.Q603Q

c.1809G>A

1 paper

NM_005474.5

p.E578K

c.1732G>A

1 paper

NM_005474.5

p.T577A

c.1729A>G

1 paper

NM_005474.5

p.D618N

c.1852G>A

1 paper

NM_005474.5

p.T552A

c.1654A>G

1 paper

NM_005474.5

p.L629_F630insFs

c.1887_1888ins11

1 paper

NM_005474.5

p.A644V

c.1931C>T