Varaico: Literature-Extracted Genetic Variants

HDAC5

138 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

HDAC4_Glnaa 67–164UCSCGlutamine rich N terminal domain of histone deacetylase 4

Hist_deacetylaa 704–1022UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 5

HGNC Alias Symbols

KIAA0600; NY-CO-9; FLJ90614

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005474.5

p.P353T

c.1057C>A

Surrounding Variants

1 paper

NM_005474.5

p.L352I

c.1054C>A

1 paper

NM_005474.5

p.S373P

c.1117T>C

1 paper

NM_005474.5

p.I341N

c.1022T>A

2 papers

NM_005474.5

p.P322A

c.964C>G

1 paper

NM_005474.5

p.V430_A431insC

c.1288_1292ins3

1 paper

NM_005474.5

p.V430_A431insCA

c.1288_1292ins6

1 paper

NM_005474.5

p.E433_G434insG

c.1297_1301ins3

1 paper

NM_005474.5

p.D435_G436insT

c.1303_1307ins3

1 paper

NM_005474.5

p.D435E

c.1305C>A

1 paper

NM_005474.5

p.S313S

c.939C>T

2 papers

NM_005474.5

p.S309F

c.926C>T

1 paper

NM_005474.5

p.Q456fs

c.1366_1367fs