Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

1–12 of 209 variants

6 papers

NM_006044.4

p.G298S

c.892G>A

4 papers

NM_006044.4

p.Q18L

c.53A>T

4 papers

NM_006044.4

p.E107E

c.321A>G

4 papers

NM_006044.4

p.A321G

c.962C>G

3 papers

NM_006044.4

p.S31S

c.93G>A

3 papers

NM_006044.4

p.K116N

c.348G>C

3 papers

NM_006044.4

p.D169G

c.506A>G

3 papers

NM_006044.4

p.R282W

c.844A>T

3 papers

NM_006044.4

p.R522G

c.1564C>G

3 papers

NM_006044.4

p.R832H

c.2495G>A

2 papers

NM_006044.4

p.G85R

c.253G>C

2 papers

NM_006044.4

p.L94F

c.282A>T