Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006044.4

p.S31S

c.93G>A

Surrounding Variants

1 paper

NM_006044.4

p.S31S

c.93G>C

1 paper

NM_006044.4

p.D26N

c.76G>A

1 paper

NM_006044.4

p.Q25Q

c.75G>A

1 paper

NM_006044.4

p.P24T

c.70C>A

4 papers

NM_006044.4

p.Q18L

c.53A>T

1 paper

NM_006044.4

p.R17W

c.49A>T

1 paper

NM_006044.4

p.R14Q

c.41G>A

1 paper

NM_006044.4

p.Q13Q

c.39G>A

1 paper

NM_006044.4

p.S31_K32Splc

c.94-27A>T

1 paper

NM_006044.4

p.T11T

c.33C>A

1 paper

NM_006044.4

p.T10A

c.28A>G

1 paper

NM_006044.4

p.S3*

c.8C>A