Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006044.4

p.V69V

c.207G>A

Surrounding Variants

1 paper

NM_006044.4

p.M74T

c.221T>C

1 paper

NM_006044.4

p.L59P

c.176T>C

1 paper

NM_006044.4

p.G54fs

c.160_161fs

1 paper

NM_006044.4

p.G54delFs

c.161delG

1 paper

NM_006044.4

p.K53R

c.158A>G

1 paper

NM_006044.4

p.K51R

c.152A>G

1 paper

NM_006044.4

p.K51M

c.152A>T

1 paper

NM_006044.4

p.K51insFs

c.151_152insC

1 paper

NM_006044.4

p.R42H

c.125G>A

1 paper

NM_006044.4

p.A39A

c.117C>T

1 paper

NM_006044.4

p.S31_K32Splc

c.94-27A>T

1 paper

NM_006044.4

p.L76M

c.226C>A