Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006044.4

p.L94F

c.282A>T

Surrounding Variants

1 paper

NM_006044.4

p.L94L

c.282A>G

1 paper

NM_006044.4

p.L94I

c.280T>A

1 paper

NM_006044.4

p.C99S

c.295T>A

1 paper

NM_006044.4

p.C99S

c.296G>C

1 paper

NM_006044.4

p.W101*

c.302G>A

1 paper

NM_006044.4

p.W101*

c.303G>A

1 paper

NM_006044.4

p.D102N

c.304G>A

1 paper

NM_006044.4

p.G87C

c.259G>T

2 papers

NM_006044.4

p.G85R

c.253G>C

1 paper

NM_006044.4

p.E81D

c.243A>C

1 paper

NM_006044.4

p.E79D

c.237G>C

1 paper

NM_006044.4

p.L76M

c.226C>A