Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006044.4

p.G298S

c.892G>A

Surrounding Variants

1 paper

NM_006044.4

p.Q299K

c.895C>A

1 paper

NM_006044.4

p.G302A

c.905G>C

1 paper

NM_006044.4

p.T304S

c.910A>T

1 paper

NM_006044.4

p.N291T

c.872A>C

1 paper

NM_006044.4

p.N306_V307delFs

c.918_919delTG

3 papers

NM_006044.4

p.R282W

c.844A>T

1 paper

NM_006044.4

p.E279K

c.835G>A

1 paper

NM_006044.4

p.Y278*

c.834C>A

1 paper

NM_006044.4

p.Y278*

c.834C>G

1 paper

NM_006044.4

p.R315W

c.943C>T

4 papers

NM_006044.4

p.A321G

c.962C>G

1 paper

NM_006044.4

p.A321V

c.962C>T