Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006044.4

p.N387D

c.1159A>G

Surrounding Variants

2 papers

NM_006044.4

p.Y386F

c.1157A>T

1 paper

NM_006044.4

p.G385D

c.1154G>A

1 paper

NM_006044.4

p.T401A

c.1201A>G

1 paper

NM_006044.4

p.P406H

c.1217C>A

1 paper

NM_006044.4

p.E383_G384Splc

c.1150-54T>A

1 paper

NM_006044.4

p.M409K

c.1226T>A

1 paper

NM_006044.4

p.A422V

c.1265C>T

1 paper

NM_006044.4

p.A374P

c.1120G>C

1 paper

NM_006044.4

p.A364T

c.1090G>A

2 papers

NM_006044.4

p.A358T

c.1072G>A

1 paper

NM_006044.4

p.E459G

c.1376A>G

1 paper

NM_006044.4

p.Q337*

c.1009C>T