Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006044.4

p.M554L

c.1660A>C

Surrounding Variants

1 paper

NM_006044.4

p.M554L

c.1660A>T

1 paper

NM_006044.4

p.A550V

c.1649C>T

1 paper

NM_006044.4

p.L559R

c.1676T>G

1 paper

NM_006044.4

p.R561S

c.1681C>A

1 paper

NM_006044.4

p.N565S

c.1694A>G

1 paper

NM_006044.4

p.D567A

c.1700A>C

2 papers

NM_006044.4

p.S568A

c.1702T>G

1 paper

NM_006044.4

p.Y570F

c.1709A>T

1 paper

NM_006044.4

p.F576F

c.1728C>T

1 paper

NM_006044.4

p.A586P

c.1756G>C

3 papers

NM_006044.4

p.R522G

c.1564C>G

1 paper

NM_006044.4

p.L508S

c.1523T>C