Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006044.4

p.Y782F

c.2345A>T

Surrounding Variants

1 paper

NM_006044.4

p.M791V

c.2371A>G

1 paper

NM_006044.4

p.T795A

c.2383A>G

1 paper

NM_006044.4

p.R810W

c.2428C>T

1 paper

NM_006044.4

p.L813L

c.2439A>G

3 papers

NM_006044.4

p.R832H

c.2495G>A

1 paper

NM_001321225.2

p.R849Q

c.2546G>A

1 paper

NM_006044.4

p.E840A

c.2519A>C

1 paper

NM_006044.4

p.E840D

c.2520A>C

1 paper

NM_006044.4

p.G844R

c.2530G>A

1 paper

NM_006044.4

p.G844R

c.2530G>C

1 paper

NM_006044.4

p.K849R

c.2546A>G

1 paper

NM_006044.4

p.T852insFs

c.2555dupC