Varaico: Literature-Extracted Genetic Variants

HDAC6

432 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 105–402UCSCHistone deacetylase domain

Hist_deacetylaa 500–798UCSCHistone deacetylase domain

zf-UBPaa 1133–1195UCSCZn-finger in ubiquitin-hydrolases and other protein

Gene Aliases

HGNC Name

histone deacetylase 6

HGNC Alias Symbols

KIAA0901; JM21; HD6; FLJ16239; PPP1R90; KDAC6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006044.4

p.A946A

c.2838C>A

Surrounding Variants

1 paper

NM_006044.4

p.A946D

c.2837C>A

1 paper

NM_006044.4

p.P948Q

c.2843C>A

1 paper

NM_006044.4

p.D963A

c.2888A>C

1 paper

NM_006044.4

p.I929T

c.2786T>C

1 paper

NM_006044.4

p.Q922*

c.2764C>T

1 paper

NM_006044.4

p.A918_T919del2

c.2752_2756del6

1 paper

NM_006044.4

p.Q978H

c.2934G>C

1 paper

NM_006044.4

p.Q978H

c.2934G>T

1 paper

NM_006044.4

p.E982G

c.2945A>G

1 paper

NM_006044.4

p.E982D

c.2946G>C

1 paper

NM_006044.4

p.E982D

c.2946G>T

1 paper

NM_006044.4

p.P910S

c.2728C>T