hepatocellular carcinoma, down-regulated 1

HEPACAM opposite strand 1

cancer susceptibility gene HEPN1

Putative cancer susceptibility gene HEPN1 protein

This gene is expressed predominantly in the liver. Transient transfection studies show the expression of this gene significantly inhibits cell growth, suggesting a role for this gene in apoptosis. Expression of this gene is down-regulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). This gene maps to the 3'-noncoding region of the HEPACAM gene (GeneID:220296) on the antisense strand. [provided by RefSeq, Aug 2020].

Varaico: Literature-Extracted Genetic Variants

HEPN1

RefSeq Summary

Gene Aliases

HGNC Name

HGNC Previous Name