Varaico: Literature-Extracted Genetic Variants

Gene:HIRA
Variant:p.G34R

HIRA

167 papers

RefSeq Summary

This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcri...

Pfam Domains

Beta-prop_CAF1B_HIR1aa 1–218UCSCCAF1B/HIR1 beta-propeller domain
Hiraaa 764–962UCSCTUP1-like enhancer of split

Gene Aliases

HGNC Name

histone cell cycle regulator

HGNC Previous Symbol

TUPLE1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_003325.4
p.G34R
c.100G>A
Surrounding Variants
4 papers
NM_003325.4
p.G34W
c.100G>T
3 papers
NM_003325.4
p.G34R
c.100G>C
1 paper
NM_003325.4
p.G34V
c.101G>T
1 paper
NM_003325.4
p.K39E
c.115A>G
1 paper
NM_003325.4
p.I42V
c.124A>G
1 paper
NM_003325.4
p.S46P
c.136T>C
1 paper
NM_003325.4
p.V48G
c.143T>G
1 paper
NM_003325.4
p.L49P
c.146T>C
1 paper
NM_003325.4
p.E51A
c.152A>C
1 paper
NM_003325.4
p.A71T
c.211G>A
1 paper
NM_003325.4
p.A71V
c.212C>T
1 paper
NM_003325.4
p.N74fs
c.220_221fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."