Varaico: Literature-Extracted Genetic Variants

HLA-DPA1

79 papers

RefSeq Summary

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a cent...

Pfam Domains

MHC_II_alphaaa 35–114UCSCClass II histocompatibility antigen, alpha domain

C1-setaa 120–201UCSCImmunoglobulin C1-set domain

Gene Aliases

HGNC Name

major histocompatibility complex, class II, DP alpha 1

HGNC Previous Symbol

HLA-DP1A

Papers

RefSeq ID

Protein change

DNA change

1–12 of 61 variants

6 papers

NM_033554.4

p.Q81R

c.242A>G

6 papers

NM_033554.4

p.L158P

c.473T>C

5 papers

NM_033554.4

p.T114A

c.340A>G

5 papers

NM_033554.4

p.F191V

c.571T>G

3 papers

NM_033554.4

p.A42T

c.124G>A

3 papers

NM_033554.4

p.A42V

c.125C>T

3 papers

NM_033554.4

p.T259P

c.775A>C

2 papers

NM_033554.4

p.R27*

c.79C>T

2 papers

NM_033554.4

p.M62L

c.184A>T

2 papers

NM_033554.4

p.M62L

c.184A>C

2 papers

NM_033554.4

p.M62K

c.185T>A

2 papers

NM_033554.4

p.M62delins

c.184_185delinsCA